Doctors using stem cells to save children with heart defects
LOS ANGELES (KABC) -- More than 35,000 babies are born with a heart defect. For many, this means a lifetime of surgery and medicine. For the first time, doctors are using stem cells to save their smallest patients and hopefully keep them off medication and out of the operating room.
Analiah Duarte was born with one of the most lethal and rare congenital heart defects; it's called Ebstein's anomaly. One of Analiah's heart valves failed to form.
"They're left with this horrible little non-functional valve that allows blood to slosh back and forth inside their heart," said Dr. Redmond Paul Burke, Chief of Pediatric Cardiovascular Surgery at Miami Children's Hospital.
Burke says it causes hearts to grow four, five, six times larger than normal.
"Analiah was born with a heart that filled her entire chest," said Burke.
Previously, surgeons would repair, replace, or close her valve, but that surgery would need to be done over and over as she grows.
"The holy grail for heart valve repair and replacement is a valve that will grow with the child," said Burke.
Doctors created that valve out of extracellular matrix-a substance extracted from a pig's bladder. The implant acts like a fishnet and captures stem cells flowing in Analiah's blood stream. The cells attach to the implant, grow around it and create a new heart valve.
"We could see, for the first time in her life, the valve that we had created opening and closing," said Burke.
A year later, Analiah's valve is working. As a result, her heart is now a third of the original size.
Dr. Burke says Analiah's new valve should grow with her throughout her life, so she won't need a transplant, surgery, or drugs. Researchers also believe this could be used in adults to replace heart valves.
health, healthy living, denise dador
- Venice beating caught on cam; suspects sought
- Baca acknowledges deputy hiring issues
- Hollywood burglary suspects caught on camera
- MoneyGram scam victims receive refund checks
- Venice boardwalk crash victims recount ordeal
- East LA coach charged with molesting 2 teens
- LAX suspect indicted on 1st-degree murder
- Yellowstone supervolcano bigger than thought
- Man kills himself, 1 other at Reno hospital
- Reporter rejects Toronto mayor's apology
- Colorado school shooter wrote plan on arm
- abcnews: Father, daughter recreate wedding photos
- Timberlake helps fan propose to girlfriend
- Photos: Meryl Streep, Julia Roberts at 'August' debut