2 of 29: Oprah Winfrey acknowledges fans during a star-studded double-taping of "Surprise Oprah! A Farewell Spectacular," Tuesday, May 17, 2011, in Chicago. "The Oprah Winfrey Show" is ending its run May 25, after 25 years, and millions of her fans around the globe are waiting to see how she will close out a show that spawned a media empire. (AP Photo/Kiichiro Sato)

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