Studies: Vitamin pills don't prevent heart disease
NEW ORLEANS -- Vitamins C and E -- pills taken by millions of Americans -- do nothing to prevent heart disease in men, one of the largest and longest studies of these supplements has found.
Vitamin E even appeared to raise the risk of bleeding strokes, a danger seen in at least one earlier study.
Besides questioning whether vitamins help, "we have to worry about potential harm," said Barbara Howard, a nutrition scientist at MedStar Research Institute of Hyattsville, Md.
She has no role in the research but reviewed and discussed it Sunday at an American Heart Association conference. Results also were published online by the Journal of the American Medical Association.
About 12 percent of Americans take supplements of C and E despite growing evidence that these antioxidants do not prevent heart disease and may even be harmful.
Male smokers taking vitamin E had a higher rate of bleeding strokes in a previous study, and several others found no benefit for heart health.
As for vitamin C, some research suggests it may aid cancer, not fight it. A previous study in women at high risk of heart problems found it did not prevent heart attacks.
Few long-term studies have been done. The new one is the Physicians Health Study, led by Drs. Howard Sesso and J. Michael Gaziano of Harvard-affiliated Brigham and Women's Hospital in Boston.
It involved 14,641 male doctors, 50 or older, including 5 percent who had heart disease at the time the study started in 1997. They were put into four groups and given either vitamin E, vitamin C, both, or dummy pills. The dose of E was 400 international units every other day; C was 500 milligrams daily.
After an average of eight years, no difference was seen in the rates of heart attack, stroke or heart-related deaths among the groups.
However, 39 men taking E suffered bleeding strokes versus only 23 of the others, which works out to a 74 percent greater risk for vitamin-takers.
The study was funded by the National Institutes of Health and several vitamin makers. Results were so clear that they would be unlikely to change if the study were done in women, minorities, or with different formulations of the vitamins, Howard said.
"In these hard economic times, maybe we can save some money by not buying these supplements," she said.
A second study found that vitamins B-12 and B-9 (folic acid) did not prevent heart disease either, supporting the results of previous trials. That study involved more than 12,000 heart attack survivors and was led by Dr. Jane Armitage of the University of Oxford in England.
- Family, police at odds over Huerta vigil violence
- One dead, one hurt in Carrboro shooting
- 'Duck Dynasty' family calls show's future into question
- Flight delayed 2 hours for pilot's sandwich delivery
- Woman rescued from crashed van
- Durham house damaged by fire
- Critical spacewalk set for Saturday
- Senate leader Harry Reid released from hospital
- Utah Attorney General to challenge end to gay marriage ban
- P.J. Hairston off the team at UNC
- Man with Down syndrome learns he's...
- Fury and frustration over Target data breach
- Power play lifts Capitals past Carolina, 4-2
- Photos: What do you do if you shopped at Target?
- abc11.com home
- Site Map
- Advertise with Us
- Contact Us
- Online Public Inspection File
- Technical Help